MTHFR is an acronym for the enzyme methylenetetrahydrofolate reductase, often referred to as “the detox gene.” The actual scope of this enzyme is much wider than the term detox gene would suggest. This enzyme is responsible for breaking down folic acid into a usable form called 5-L-methyltetrahydrofolate, and is coded primarily in the two genes C677T and A1298C. 2

When this enzyme can’t be produced or is diminished because of this mutation or a partial mutation then lots of important physiology is disrupted. This mutation hinders methylation in the body. Methylation is required by every cell in our body and occurs billions of times per second.

Areas negatively impacted include DNA repair, immune function, detoxification, neurotransmitter production, hormone regulation, mood balancing, energy production and more.3

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